What is follicular lymphoma?
Follicular lymphoma is a different disease in every person. Most people have a slow-growing tumor that responds well to available therapies, while others have a faster-growing, hard-to-treat type of follicular lymphoma.
Who gets follicular lymphoma?
What are the symptoms of follicular lymphoma?
How is follicular lymphoma diagnosed?
Once follicular lymphoma is diagnosed, your doctor will determine the stage of the tumor by assessing how many nodes or other sites are affected. Early stage disease is generally localized to one area and does not cause symptoms, while advanced-stage disease has spread further in the body and may cause symptoms. Other risk factors—age, anemia, levels of other molecules in the blood—can predict behavior of the disease and may help your doctor determine the best treatment.
How is early stage follicular lymphoma treated?
How is advanced-stage follicular lymphoma treated?
Patients who are not experiencing symptoms from the tumor may be monitored with a “watch-and-wait” approach, which has been shown to be a safe strategy in patients with advanced-stage disease.
When the tumor progresses and becomes symptomatic, patients are likely to receive a regimen of chemotherapy in combination with rituximab, an antibody that binds to B-cells, including follicular lymphoma cells.
What happens after treatment is completed?
You and your doctor should continue to monitor for the disease in the years after treatment by examining lymph nodes and targeted organs, reviewing any symptoms associated with the disease, and having regular bloodwork done.
References
- Freedman AS. Follicular lymphoma: 2015 update on diagnosis and management. Am J Hematol. 2015;90:1172-1178.
- Hiddemann W, Cheson BD. How we manage follicular lymphoma. Leukemia. 2014;28:1388-1395.
- Salles GA. Clinical features, prognosis and treatment of follicular lymphoma. Hematology Am Soc Hematol Educ Program. 2007;216-222.
- Schatz JH, Oricchio E, Puvvada SD, Wendel HG. Progress against follicular lymphoma. Curr Opin Hematol. 2013;20:320-326.
- Zelenetz AD, Abramson JS, Advani RH, et al. Non-Hodgkin’s lymphomas. J Natl Compr Cancer Netw. 2011;9:484-560.